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Angpt2 Antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - Angpt2 Antibody - middle region AI14929

    Host: Rabbit
    Target Name: Angpt2
    Sample Tissue: Mouse Liver lysates
    Antibody Dilution: 1.0μg/ml
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession O35608
Other Accession NM_007426, NP_031452
Reactivity Human, Mouse, Rat, Rabbit, Pig, Sheep, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Sheep, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 56kDa
Additional Information
Gene ID 11601
Alias Symbol Agpt2, Ang-2, Ang2
Other Names Angiopoietin-2, ANG-2, Angpt2, Agpt2
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Angpt2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsAngpt2 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Angpt2
Synonyms Agpt2
Function Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling (By similarity). Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1 (By similarity). In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression (By similarity). In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal (By similarity). Involved in the regulation of lymphangiogenesis (PubMed:28179430, PubMed:32908006).
Cellular Location Secreted {ECO:0000250|UniProtKB:O15123}.
Tissue Location Expressed in the ovary, uterus and placenta.
Research Areas
Citations (0)
citation

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References

Maisonpierre P.C.,et al.Science 277:55-60(1997).
Carninci P.,et al.Science 309:1559-1563(2005).

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$ 389.00
Cat# AI14929
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